Abstract #3159

Optimized Acquisition for Joint T2 and ADC mapping in the Heart

Zhaohuan Zhang^1,2, Eric Aliotta^2,3, and Daniel B Ennis^2,3

¹Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China, People's Republic of, ²Department of Radiological Sciences, University of California, Los Angeles, CA, United States, ³Physics & Biology in Medicine Graduate Program, University of California, Los Angeles, CA, United States

Myocardial T₂ and Apparent Diffusion Coefficient (ADC) can be used to evaluate the presence of edema and myocardial infarction^1,2. We recently developed a technique for joint acquisition and reconstruction of T₂ and ADC maps using a spin-echo EPI diffusion weighted sequence (SE-EPI DWI) with a total acquisition time short enough to accommodate measurement in a single breath-hold. The objective of this study was to optimize the joint T₂/ADC acquisition to enhance sensitivity to myocardial infarction and to evaluate performance in simulations and phantom experiments.

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