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Abstract #3159

Optimized Acquisition for Joint T2 and ADC mapping in the Heart

Zhaohuan Zhang1,2, Eric Aliotta2,3, and Daniel B Ennis2,3

1Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China, People's Republic of, 2Department of Radiological Sciences, University of California, Los Angeles, CA, United States, 3Physics & Biology in Medicine Graduate Program, University of California, Los Angeles, CA, United States

Myocardial T2 and Apparent Diffusion Coefficient (ADC) can be used to evaluate the presence of edema and myocardial infarction1,2. We recently developed a technique for joint acquisition and reconstruction of T2 and ADC maps using a spin-echo EPI diffusion weighted sequence (SE-EPI DWI) with a total acquisition time short enough to accommodate measurement in a single breath-hold. The objective of this study was to optimize the joint T2/ADC acquisition to enhance sensitivity to myocardial infarction and to evaluate performance in simulations and phantom experiments.

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