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Abstract #3206

Modelling intra-voxel dephasing in MR simulations

Stefan Kroboth1, Katharina E. Schleicher1, Kelvin J. Layton1, Axel J. Krafft1,2,3, Klaus Düring4, Feng Jia1, Sebastian Littin1, Huijun Yu1, Jürgen Hennig1, Michael Bock1, and Maxim Zaitsev1

1Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 2German Cancer Consortium (DKTK), Heidelberg, Germany, 3German Cancer Research Center (DKFZ), Heidelberg, Germany, 4MaRVis Medical GmbH, Hannover, Germany

In order to capture intra-voxel dephasing in simulations, the object has to be modeled with a very large number of spins per voxel. We present a method to improve and speed up simulations by explicitly modelling intra-voxel dephasing. The method is evaluated by simulating an MR-safe guidewire. The iron particles in the wire create dipole fields, which lead to dephasing in the proximity of the wire. We show that a substantial reduction of the required number of spins by a factor of ~5.4 is possible, without sacrificing image quality. This reduces the memory requirements and speeds up simulations.

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