Abstract #3206

Modelling intra-voxel dephasing in MR simulations

Stefan Kroboth¹, Katharina E. Schleicher¹, Kelvin J. Layton¹, Axel J. Krafft^1,2,3, Klaus Düring⁴, Feng Jia¹, Sebastian Littin¹, Huijun Yu¹, Jürgen Hennig¹, Michael Bock¹, and Maxim Zaitsev¹

¹Medical Physics, University Medical Center Freiburg, Freiburg, Germany, ²German Cancer Consortium (DKTK), Heidelberg, Germany, ³German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁴MaRVis Medical GmbH, Hannover, Germany

In order to capture intra-voxel dephasing in simulations, the object has to be modeled with a very large number of spins per voxel. We present a method to improve and speed up simulations by explicitly modelling intra-voxel dephasing. The method is evaluated by simulating an MR-safe guidewire. The iron particles in the wire create dipole fields, which lead to dephasing in the proximity of the wire. We show that a substantial reduction of the required number of spins by a factor of ~5.4 is possible, without sacrificing image quality. This reduces the memory requirements and speeds up simulations.

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