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Abstract #3213

Improved Assessment of Left Ventricular Diastolic Function using High-Temporal Cine-CMR

Keigo Kawaji1, Mita B. Patel1, Marco Marino1, Roberto M. Lang1,2, Hui Wang3, Yi Wang4, and Amit R. Patel1,2

1Medicine, The University of Chicago, Chicago, IL, United States, 2Radiology, The University of Chicago, Chicago, IL, United States, 3Philips Healthcare, Cleveland, OH, United States, 4Biomedical Engineering and Radiology, Cornell University, New York, NY, United States

Assessment of diastolic function using cine-CMR is limited by its temporal resolution. A high-temporal cine-CMR approach that yields comparable temporal resolution to echocardiography was recently developed using radial trajectories with a custom spoke ordering that exploits the property of prime numbers (Modulo-Prime Spokes, or MoPS), as well as a radial UNFOLD-type streaking artifact removal step. In this study, we validate the functional cine-assessment parameters associated with systolic and diastolic performance of the left ventricle (LV) by comparing the measurements derived from time-volume curves between the proposed radial MoPS-Cine and the clinically employed Cartesian Cine reference.

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