Abstract #3243

Simultaneously Multi-Slice (SMS) Accelerated Interleaved EPI DWI using 3D K-space Reconstruction

Erpeng Dai¹, Xiaodong Ma¹, Zhe Zhang¹, Chun Yuan^1,2, and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, ²Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

Simultaneously multi-slice (SMS) has been a powerful tool for single-shot EPI DWI acceleration, but still not well established for interleaved EPI (iEPI) DWI acceleration. The main challenge is how to effectively combine slice un-folding and inter-shot phase correction. In this study, a 3D k-space reconstruction method for navigated SMS accelerated iEPI DWI has been proposed. An optimized acquisition for navigator is designed. Then slice un-folding and inter-shot phase correction are performed in a SMS 3D k-space. The performance is compared with ssEPI and un-accelerated iEPI DWI, and has been shown to be applicable for both 4-sh and 8-sh iEPI DWI.

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