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Abstract #3246

Echo-Shift wave-CAIPI with Simultaneous MultiSlice imaging for rapid susceptibility weighted FLASH

Huihui Ye1,2, Berkin Bilgic1, Stephen Cauley1, Borjan Gagoski3, Jianghui Zhong2, Yiping Du2, Lawrence L. Wald1, and Kawin Setsompop1

1MGH/A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2Zhejiang University, Hangzhou, China, People's Republic of, 3Boston Children's Hospital, Charlestown, MA, United States

Susceptibility weighted FLASH imaging provides exquisite soft tissue contrast at high spatial resolution and low distortion, but at a cost of lengthy acquisition time. In this work, we developed a highly efficient Echo-Shift wave-CAIPI technique and demonstrated its ability to provide 18-fold acceleration for FLASH acquisitions with minimal noise and artifact penalties. Instead of conventional single slice or slab echo-shift, we propose an echo-shift Simultaneous MultiSlice method to enable improved controlled aliasing and desirable volumetric noise averaging while avoiding slab edge artifacts. With this technique, we demonstrated high-quality 1.5 mm isotropic whole-brain susceptibility weighted FLASH at 3T and 7T in 36s.

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