Abstract #3246

Echo-Shift wave-CAIPI with Simultaneous MultiSlice imaging for rapid susceptibility weighted FLASH

Huihui Ye^1,2, Berkin Bilgic¹, Stephen Cauley¹, Borjan Gagoski³, Jianghui Zhong², Yiping Du², Lawrence L. Wald¹, and Kawin Setsompop¹

¹MGH/A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ²Zhejiang University, Hangzhou, China, People's Republic of, ³Boston Children's Hospital, Charlestown, MA, United States

Susceptibility weighted FLASH imaging provides exquisite soft tissue contrast at high spatial resolution and low distortion, but at a cost of lengthy acquisition time. In this work, we developed a highly efficient Echo-Shift wave-CAIPI technique and demonstrated its ability to provide 18-fold acceleration for FLASH acquisitions with minimal noise and artifact penalties. Instead of conventional single slice or slab echo-shift, we propose an echo-shift Simultaneous MultiSlice method to enable improved controlled aliasing and desirable volumetric noise averaging while avoiding slab edge artifacts. With this technique, we demonstrated high-quality 1.5 mm isotropic whole-brain susceptibility weighted FLASH at 3T and 7T in 36s.

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