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Abstract #3260

Optimization of High-Resolution Slice-Accelerated Inversion Recovery T1 Mapping at 7T

John Grinstead1, Valerie Anderson2, Manoj Sammi2, and William Rooney2

1Siemens Healthcare, Portland, OR, United States, 2Oregon Health & Science University, Portland, OR, United States

Parametric T1 mapping using inversion recovery has competing requirements for speed, SNR, spatial resolution, anatomical coverage, and adequate sampling of the longitudinal magnetization recovery. Potential sources of slice-to-slice variability in quantitative T1 maps are investigated, including slice cross talk due to imperfect slice profiles, and the range of TIs used to fit each slice. It is demonstrated that T1 relaxometry benefits significantly from slice acceleration techniques in not only scan time & slice coverage, but in its ability to reduce quantitative errors by allowing the same TI sampling across all slices.

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