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Abstract #3308

3D arterial spin labeling imaging with DANTE preparation pulse

Tsuyoshi Matsuda1, Hirohiko Kimura2, Masayuki Kanamoto3, and Hiroyuki Kabasawa1

1MR Applications and Workflow, GE Healthcare Japan Corporation, Tokyo, Japan, 2Department of Radiology, University of Fukui, Fukui, Japan, 3Radiological Center, University of Fukui Hospital, Fukui, Japan

DANTE preparation pulse for the arterial spin-labeling (ASL) sequence was developed to reduce the intravascular signal based on the hypothesis that DANTE could enable sufficient vascular signal suppression without any technical drawback. Phantom and human volunteer experiments were performed to evaluate the proposed method. A similar level of vascular suppression effect was observed with both MSDE and DANTE-prepared ASL sequence from phantom experiment. A signal intensity uniformity of vascular suppressed perfusion weighted images was superior with DANTE compared to MSDE. These results indicated that DANTE-preparation could be used as a vessel signal suppression method for ASL.

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