Abstract #3331

REPLICABILITY OF CEREBRAL PERFUSION WITH DIFFERENT ARTERIAL SPIN LABELLING METHODS

ZHE HAN TOH¹, WENG HANG WONG¹, QING LONG GU¹, KAI-HSIANG CHUANG², KUAN-JIN LEE², JULIAN GAN³, and PHUA HWEE TANG¹

¹Department of Diagnostic and Interventional Imaging, KK WOMEN'S AND CHILDREN'S HOSPITAL, SINGAPORE, Singapore, ²Singapore Bio-Imaging Consortium, A*STAR, SINGAPORE, Singapore, ³Siemens Healthcare, Regional Headquarter, SINGAPORE, Singapore

We compared 3 versions of Arterial Spin Labelling (ASL) available ( single-TI 3D-PASL, multi-TI 3D-PASL and 2D-pCASL) on 3T Siemens MRI scanner Skyra in 10 normal healthy adults with normal body mass index (BMI) at 3 different time points (baseline, 1 week later, 2 to 3 month later). There was good replicability of all 3 ASL techniques (correlation coefficients range from 0.55 to 0.77). Values acquired with these ASL techniques agree with the published normal range of cerebral blood flow values in adults. There is no significant difference in the CBF obtained with single-TI 3D-PASL, multi-TI 3D-PASL and 2D-pCASL.

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