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Abstract #3344

Cerebral Arterial Inflow and Venous Outflow: Flow Discrepancy and Relation to Cardiac Outflow in Children and Adult Volunteers

Can Wu1,2, Susanne Schnell2, Ryan Kuhn3, Samantha E Schoeneman4, Amir R Honarmand2, Michael Markl1,2, and Ali Shaibani2,3

1Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, 2Department of Radiology, Northwestern University, Chicago, IL, United States, 3Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, 4Rush Medical College, Chicago, IL, United States

Abnormal cerebral venous outflow patterns may cause severe cerebrovascular disease. We aim to investigate the relationships between cerebral venous outflow and arterial inflow and between cerebral arterial inflow and cardiac outflow in adult and children volunteers using 4D flow and 2D phase-contrast MRI. The results demonstrate significant discrepancies between cerebra arterial inflow and venous outflow with larger discrepancies in children than adults. Additionally, we observed a significantly association of cerebral and cardiac flow parameters with age.

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