Abstract #3347

Quantification of the effect of head-down tilt posture on intracranial condition using MRI

Naoki Ohno¹, Tosiaki Miyati¹, Shinnosuke Hiratsuka², Shota Ishida³, Noam Alperin⁴, Satoshi Kobayashi¹, and Toshifumi Gabata⁵

¹Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, ²Department of Radiology, Shiga University of Medical Science Hospital, Otsu, Japan, ³Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan, ⁴Department of Radiology, University of Miami, Miami, FL, United States, ⁵Department of Radiology, Kanazawa University, Kanazawa, Japan

To quantify the effect of posture on intracranial condition, we assessed intracranial volume change (ΔICVC), pressure gradient (ΔPG), intracranial compliance index (ICCI), and apparent diffusion coefficient (ADC) change of the brain during the cardiac cycle (ΔADC) in head-down tilt (HDT) and horizontal supine positions. ΔPG was significantly increased on HDT compared with that in the horizontal supine position because of the intracranial pressure compensatory mechanism. However, there were no significant differences in other parameters between postures. ΔPG analysis in the HDT and horizontal supine positions makes it possible to evaluate intracranial conditions concerning the intracranial pressure compensatory faculty.

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