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Abstract #3455

Histogram analysis of apparent diffusion coefficient in characterizing solid pancreatic masses

Yoshihiko Fukukura1, Toshikazu Shindo1, Yuichi Kumagae1, Koji Takumi1, Hiroto Hakamada1, Masanori Nakajo1, and Takashi Yoshiura1

1Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

This study focused on the potential of ADC histogram analysis on DW imaging to characterize solid pancreatic masses. Among the ADC histogram parameters, the entropy of ADC with every b-value combination showed the highest area under the receiver operating characteristic curve for distinguishing neuroendocrine tumors from pancreatic adenocarcinomas and mass-forming autoimmune pancreatitis. The entropy of ADC might add helpful information in differentiating neuroendocrine tumors from pancreatic adenocarcinomas and mass-forming autoimmune pancreatitis, especially in patients with contraindication to contrast agents or with solid pancreatic masses showing atypical findings at dynamic CT or MRI.

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