Abstract #3461

Implementing a fast MR screening protocol for pancreas in patients with mutations of BRCA1 and BRCA2: preliminary data on Diffusion-Weighted Images.

Andrea Agostini¹, Mitchell Raeside¹, Richard Do¹, Amita Shukla-Dave², David Aramburu Nunez², Ramesh Paudyal², Olga Smelianskaia¹, Maggie Fung³, Monika Khan¹, David Kelsen⁴, Gabriella Carollo⁵, and Lorenzo Mannelli¹

¹Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, United States, ²Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY, United States, ³Global MR Applications and Workflow, GE Healthcare, New York, NY, United States, ⁴Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, United States, ⁵Saint Vincent Ferrer High School, New York, NY, United States

The aim of the study is the qualitative and quantitative evaluation of Diffusion-weighted images (DWI) with reduced field-of-view (rFOV), that are incorporated into a fast rapid MR pancreas screening protocol (MRpsp). We are developing a fast rapid MRpsp to be performed in carriers of BRCA mutations after a breast MRI, using the built-in body coil of a 3T magnet without repositioning a patient who is in the prone position. 15 patients were scanned. For b-values <100 s/mm², b=20 s/mm² DWI had the best contrast-to-noise and signal-to-noise ratios. Among b-values >100 s/mm², b=250 s/mm² DWI showed the highest diagnostic information.

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