Abstract #3463

Repeatability on diffusion MRI measurements on the different numbers of b values and excitations of the breast and its comparison with lactating breasts

Mami Iima^1,2, Masako Kataoka¹, Shotaro Kanao¹, Natsuko Onishi¹, Makiko Kawai¹, Akane Ohashi¹, Rena Sakaguchi¹, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Graduate Schoolof Medicine, Kyoto University, Kyoto, Japan, ²The Hakubi Center for Advancer Research, Kyoto University, Kyoto, Japan

The effects of different numbers of b values and excitations on the non-Gaussian DWI parameter estimates in the breast of normal volunteers was assessed. A good agreement of Do, K and synthetic ADC200-1500 was observed among different number of b values as well as excitations. Lower Do and sADC200-1500 were found in women with lactation period. Higher K and fIVIM were observed in lactating volunteers with some overlap. A limited protocol using only 5 b values could be relevant in clinical setting, resulting in a remarkable reduction in acquisition time.

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