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Abstract #3463

Repeatability on diffusion MRI measurements on the different numbers of b values and excitations of the breast and its comparison with lactating breasts

Mami Iima1,2, Masako Kataoka1, Shotaro Kanao1, Natsuko Onishi1, Makiko Kawai1, Akane Ohashi1, Rena Sakaguchi1, and Kaori Togashi1

1Department of Diagnostic Imaging and Nuclear Medicine, Graduate Schoolof Medicine, Kyoto University, Kyoto, Japan, 2The Hakubi Center for Advancer Research, Kyoto University, Kyoto, Japan

The effects of different numbers of b values and excitations on the non-Gaussian DWI parameter estimates in the breast of normal volunteers was assessed. A good agreement of Do, K and synthetic ADC200-1500 was observed among different number of b values as well as excitations. Lower Do and sADC200-1500 were found in women with lactation period. Higher K and fIVIM were observed in lactating volunteers with some overlap. A limited protocol using only 5 b values could be relevant in clinical setting, resulting in a remarkable reduction in acquisition time.

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