Imaging bio-markers of Intervertebral disc degeneration by T2 Relaxometry and DTI A prospective Study with Multi parametric Imaging correlation
rammohan sai venkata vadapalli1, Raghav dutt sai venkata Mulukutla2, and abhinav sriiram Vadapalli3
1Imaging, Vijaya diagnostics and research, Hyderabad 500020, India, 2Orthopaedic and Spine surgery, Udai orthopaedic Institute, Hyderabad 500020, India, 3Imaging, GH, Hyderabad 500020, India
Surgeons
want to know Predictive disc health proximal to the level of fusion or
intervention.
Conventional
MR imaging using T2 weighted Imaging is insensitive to early morphological
changes with no predictive quantitative biomarker profile of early
degeneration.
The
Thompson scale or the Pfirrmann scale are discontinuous scales fail to
demonstrate the Degeneration or regeneration of disc Objectively.
Multiparametric Imaging using T2 relaxometry
maps,DTI indices namely FA and qualitative FA maps offer both quantitative and
qualitative biomarkers for predictive disc health
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