Abstract #3475

Imaging bio-markers of Intervertebral disc degeneration by T2 Relaxometry and DTI A prospective Study with Multi parametric Imaging correlation

rammohan sai venkata vadapalli¹, Raghav dutt sai venkata Mulukutla², and abhinav sriiram Vadapalli³

¹Imaging, Vijaya diagnostics and research, Hyderabad 500020, India, ²Orthopaedic and Spine surgery, Udai orthopaedic Institute, Hyderabad 500020, India, ³Imaging, GH, Hyderabad 500020, India

Surgeons want to know Predictive disc health proximal to the level of fusion or intervention. Conventional MR imaging using T2 weighted Imaging is insensitive to early morphological changes with no predictive quantitative biomarker profile of early degeneration. The Thompson scale or the Pfirrmann scale are discontinuous scales fail to demonstrate the Degeneration or regeneration of disc Objectively. Multiparametric Imaging using T2 relaxometry maps,DTI indices namely FA and qualitative FA maps offer both quantitative and qualitative biomarkers for predictive disc health

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