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Abstract #3477

The Study of Vertebral Marrow Microstructure in Healthy Young Adults with Intravoxel Incoherent Motion Diffusion-weighted Imaging

Jinliang Niu1, Wenqi Wu1, Tong Gong1, Wenjin Li1, Dandan Zheng2, Zheng Zhong3, Hongwei Wang1, and Xiaohong Joe Zhou3

1The Second Hospital of Shanxi Medical University, Taiyuan, China, People's Republic of, 2GE Healthcare MR Research China, Beijing, China, People's Republic of, 3Center for Magnetic Resonance Research, University of Illinois Hospital &Health Sciences System, Chicago, IL, United States

MRI has become preferred over other imaging modalities in evaluating marrow compositions. Although the routine MRI can evaluate the cellularity of marrow according to signal intensity, it’s not quantitative analysis. IVIM provides both diffusion and perfusion quantification using a single imaging study at the same time, without intravenous contrast injection. IVIM has been applied in various diseases, but the application of IVIM in marrow composition is less. As the preliminary study, we will adopt the parameters of IVIM to assess the vertebral bone marrow microstructure, then to investigate gender-related cellular and capillary network of vertebral marrow in healthy young adults.

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