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Abstract #3493

Evaluation of Acute Cerebral Infarction Using a Fast Kurtosis Diffusion imaging Protocol

Chengxu Li1, Tianyi Qian2, Jinsuh Kim3, Philip Zhe Sun4, Jie Lu1, and Kuncheng Li1

1Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of, 2MR Collaborations NE Asia, Siemens Healthcare, Beijing, China, People's Republic of, 3Department of Radiology, University of Illinois at Chicago, Chicago, IL, United States, 4Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

Conventional DKI is limited in use for detecting acute stroke because of its relatively long scan time and current need of offline processing. Here we used a 13 directions protocol combined with simultaneous multi-slice technique with inline reconstruction to test the diffusion pattern at different time points. The results shows the lesion size observed within 24hr on MK matched with the lesion size on T2-FLAIR after one month, which was better than lesion size observed within 24hr on DWI. Early application of the fast DKI to detect the anomalous range of MK was beneficial to predict the range of the eventual infarction for clinical treatment.

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