Abstract #3495

Diffusional Kurtosis Imaging Study Of Parkinson Disease

Xilun Ma¹, Jitian Guan¹, Zhiyan Zhang¹, Miaomiao Chen¹, Yanzi Chen¹, Zhiwei Shen¹, and Renhua Wu¹

¹Department of Medical Imaging, the 2nd Affiliated Hospital, Medical College of Shantou University, Shantou 515041, China, Shantou, China, People's Republic of

Eighteen Parkinson Disease’s (PD) patients and four healthy controls(HC) underwent the diffusional kurtosis imaging (DKI) and then we tested the PD’s patients with Hoehn-Yahr scale and Unified Parkinson Disease Rating Scale(UPDRS). As a result, we found a significant decrease of Mean kurtosis (MK) values in the left substantia nigra between PD’s patients and healthy controls. Moreover, the kurtosis fractional anisotropy (KFA) values in right red nucleus of the PD’s patients were positively associated with the UPDRS scores in our study.

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