Abstract #3519

Assessment of coil arrays with small loop diameter at 7T for micron-scale resolution fMRI of human neocortex.

Alexander Beckett¹, An T Vu^1,2, Boris Keil³, Kawin Setsompop³, Lawrence L Wald³, Scott Schillak⁴, and David A Feinberg^1,2

¹Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States, ²Advanced MRI Technologies, Sebastopol, CA, United States, ³Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ⁴Virtumed, LLC, Minneapolis, MN, United States

The use of array coils with smaller loop sizes allows increased signal to noise ratio close to the coils with decreased coverage of the brain. By focusing on cortical imaging (MR Corticography, MRCoG), this increased SNR can be leveraged to allow ultra-high resolution neuroimaging and fMRI. We assess array coils with varying loop sizes (50mm-20mm) in phantom and with 8-channel arrays (70mm, 40mm, 30mm) in brain at ultra-high resolution (≤ 500 micron isotropic voxels), and show increases in SNR and BOLD contrast in the human cortex as loop size decreases.

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