Abstract #3523

Sensitive detection of hemodynamic responses to TMS pulse at human sensorimotor cortex

Pu-Yeh Wu¹, Ying-Hua Chu¹, Aapo Nummenmaa², Thomas Witzel², Shang-Yueh Tsai³, Wen-Jui Kuo⁴, and Fa-Hsuan Lin¹

¹Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Institute of Applied Physics, National Chengchi University, Taipei, Taiwan, ⁴Institute of Neuroscience, National Yang Ming University, Taipei, Taiwan

We tested how TMS pulses and the separation between TMS pulse and RF excitation affect MRI SNR and tSNR using our tailored 8-channel TMS-compatible MRI coil array. Result from an in vivo experiment using this integrated system to record the BOLD signal elicited by TMS pulses at human primary motor cortex is also reported.

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