Abstract #3620

55Mn Fiducial Markers for Automated Coil Localization and Sensitivity Determination for Use With Hyperpolarized 13C MRI

Michael Ohliger¹, Cornelius von Morze¹, Lucas Carvajal¹, Irene Marco-Rius¹, Jao Ou¹, and Daniel Vigneron¹

¹Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

RF coil arrays are critically important for hyperpolarized C-13 imaging because of increased sensitivity, coverage, and speed. A major limitation preventing widespread use of coil arrays is the difficulty measuring coil sensitivity profiles due to low C-13 natural abundance. We propose to solve this problem by using fiducial markers filled with 55Mn to determine coil location and then calculate coil sensitivities. We show proof-of-principle using a single RF coil and ethylene glycol phantom. Coil sensitivties derived from fiducial markers and quasitstatic calculations closely match those acquired through experiment.

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