Abstract #3657

Potential Effects of MR-induced Temperature Increase on PET Signal during MR/PET: Simulations of a Worst-Case Scenario

Giuseppe Carluccio^1,2, Yu-Shin Ding^1,2, Jean Logan^1,2, and Christopher Michael Collins^1,2

¹Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), New York, NY, United States, ²Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, United States

We explore the possibility that SAR-related temperature increase could affect metabolic rates enough to alter FDG signal in MR/PET. Using numerical simulations, we calculate the distributions of SAR, temperature, metabolic rates, FDG concentration ([FDG]), and PET signal throughout the human body. Calculation of [FDG] utilizes a two-compartment model considering metabolic rate through time. Results are calculated for injection time one hour before the onset of imaging and for injection time simultaneous with the onset of imaging. Even for worst-case scenario (max allowable whole-body SAR for the duration of the scan), there is little observable effect on PET signal.

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