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Abstract #3714

A Comparison between the UTE and PETRA Pulse Sequences for Fluorine-19 MRI at 3 Tesla

Roberto Colotti1, Jean Delacoste1, Giulia Ginami1, Maxime Pellegrin2, Tobias Kober1,3,4, Yutaka Natsuaki5, David Grodzki6, Ulrich Flögel7, Matthias Stuber1,8, and Ruud B. van Heeswijk1

1Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Division of Angiology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland, 3Advanced Clinical Imaging Technology, Siemens Healthcare IM BM PI, Lausanne, Switzerland, 4LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 5Siemens Medical Solutions, NAM USA DI MR COLLAB WE, Los Angeles, CA, United States, 6Siemens Healthcare GmbH, HC DI MR R&D PLH, Erlangen, Germany, 7Department of Cardiovascular Physiology, Heinrich Heine University, Düsseldorf, Germany, 8Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Fluorine-19 (19F) MRI of perfluorocarbon emulsions (PFCs) with multiresonant spectra is challenging due to destructive phase interference that leads to short T2 relaxation times (<10 ms). Pulse sequences with very short echo times (≤ 100 µs) can be used to overcome this challenge. In this study, in vitro and in vivo 19F MRI obtained with both UTE and PETRA were acquired and quantitatively compared.

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