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Abstract #3810

A Brain Resting State network specific T2* Study in neonatal infants

Maryam Abaei1, Tomoki Arichi1,2, Anthony Price1, Eugene P Duff3, Emer Hughes1, Giulio Ferrazzi1, Jacques-Donald Tournier 1, Jonathan O'Muircheartaigh1,4, Serena Counsell1, A David Edwards1,5, Steve M Smith3, Daniel Rueckert6, and Joseph V Hajnal1,5

1Centre for the Developing Brain, King's College London, London, United Kingdom, 2Department of Bioengineering, Imperial College, London, United Kingdom, 3Department of Clinical Neurosciences, Oxford University, Oxford, United Kingdom, 4Institute of Psychiatry, Kings College London, London, United Kingdom, 5Division of Imaging Sciences and Biomedical, King's College London, London, United Kingdom, 6Biomedical Image Analysis Group, Department of Computing, Imperial College, London, United Kingdom

Previous studies reported that, although the majority of RSNs are present at the time of normal birth, but they appear to mature at different rates with the "higher-order" networks developing later than primary sensory. T2* in neonates are up to 2 times longer than those typically seen in the mature adult brain and decrease with increasing gestational age at scan. In this study we assessed T2* for different RSNs and hypothesized that those which mature earlier on structural MRI would have shorter T2* than networks in cortical regions that develop later in gestation.

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