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Abstract #3834

A Systematic Investigation on the BOLD Contrast in S1- and S2-SSFP fMRI

Mahdi Khajehim1 and Abbas Nasiraei Moghaddam1,2

1Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran, 2School of Cognitive Sciences, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran

Non-balanced SSFP can provide banding artifact free images, with reduced sensitivity to B1 inhomogeneity and SAR level. Recently, non-balanced SSFP which is known by the S1 and S2 signals, has been utilized for fMRI. In this study to model the BOLD contrast in S1- and S2-SSFP fMRI a Monte Carlo simulation has been performed. It will enable us to accurately investigate the dependence of the BOLD contrast on vessel size and acquisition parameters. Results are in accordance with the reported experimental values and show the increased sensitivity to capillary-sized vessels for only S2 signal.

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