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Abstract #3868

Fast T2 mapping for the diagnosis of prostate cancer by using 3.0T MRI

Danyan Li1, Qinglei Zhang1, Harsh K Agarwal2, Weibo Chen2, and Bin Zhu1

1Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China, People's Republic of, 2Philips Research NA, Cambridge, MA, MA, United States

Quantitative T2 values has the potential to reliably and reproducibly differentiate prostate abnormalities,such as prostate cancer (PCa) , benign prostate hyperplasia(BPH)and normal prostate tissue (NPT). We used k-t-T2 technique to obtain the T2 maps and tested the diagnostic performance of T2 mapping in differentiating PCa from NPT and BPH in the peripheral zone.We found the T2 values is quite useful for cancer discrimination with, for example, a threshold T2 of 68.3 ms yielded a sensitivity of 94% and a specificity of 98% for PCa discrimination.

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