Abstract #3872

Body Composition Analysis In Large Scale Population Studies using Dixon Water-Fat Separated Imaging

Janne West^1,2, Olof Dahlqvist Leinhard^1,2, Thobias Romu^2,3, E. Louise Thomas⁴, Magnus Borga^2,3, and Jimmy D. Bell⁴

¹Department of Medical and Health Sciences (IMH), Linköping University, Linköping, Sweden, ²Center for Medical Image Science and Visualization (CMIV), Linköping, Sweden, ³Department of Biomedical Engineering, Linköping University, Linköping, Sweden, ⁴Department of Life Sciences Faculty of Science and Technology, University of Westminster, London, United Kingdom

Water-fat separated MRI, based on Dixon imaging techniques enables high soft-tissue contrast and the separation of fat and muscle compartments. This study investigate the feasibility and success-rate of one recently described method for MR data-acquisition and body composition analysis, in a large-scale population study. The first 1,000 subjects in the UK Biobank imaging cohort were scanned, quality assured and included for body composition analysis. Volumes of visceral adipose tissue, abdominal subcutaneous tissue, and thigh muscles were calculated. This study showed that the rapid MR-examination was sufficiently robust to achieve very high success-rate for body composition analysis.

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