Abstract #3939

A Comparison of Rapid Acquisition Sodium T1 Mapping Techniques at 3T

James Grist¹, Martin J Graves¹, Josh Kaggie¹, Mary Mclean², Frank Riemer¹, and Ferdia A Gallager¹

¹Radiology, University of Cambridge, Cambridge, United Kingdom, ²Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom

Sodium T₁ maps from three different Variable Flip Angle (VFA) methods were assessed against Inversion Recovery (IR) data, showing that the estimated method of slopes (eMOS) is superior to both linear and non-linear fitting methods in the healthy brain. eMOS requires two flip angle data sets to produce volumetric T₁ maps of the brain, in comparison to other techniques which require 4 or more data sets to produce maps, and therefore allows for shortening of the overall time spent scanning. Furthermore, T₁ maps may also give further insight in to the underlying tissue structure surrounding sodium nuclei.

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