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Abstract #4138

Altered cortical thickness related to the SNPs on the major histocompatibility complex in never-medicated schizophrenia

Bo Tao1, Yuan Xiao1, Lu Liu1, Li Yao1, Wenjing Zhang1, and Su Lui1

1Radiology, West China Hospital of SiChuan University, Chengdu, China, People's Republic of

In summary, the present study provided evidence that single nucleotide polymorphisms(SNPs) on the major histocompatibility (MHC) relate with cortical thickness deficits in several regions,which support the critical role of immune system in the pathology of schizophrenia via modulation the development of the cerebral cortical structure.

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