Meeting Banner
Abstract #4213

Accelerating MR measurement of liver steatosis using combined compressed sensing and parallel imaging: quantitative evaluation for clinical trials

Louis W Mann1, David M Higgins2, Carl N Peters1, Sophie Cassidy1, Ken K Hodson1, Anna Coombs1, Roy Taylor1, and Kieren Grant Hollingsworth1

1Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, 2Philips Healthcare, Guildford, United Kingdom

We compared hepatic fat fractions quantified with accelerated magnetic resonance (MR) imaging reconstructed with combined compressed sensing and parallel imaging (CS-PI) with conventional acquisitions. Undersampled data at ratios of 2.6×, 2.9×, 3.8×, and 4.8× were prospectively acquired from eleven subjects with type 2 diabetes and a healthy control. Fat fraction maps were calculated using CS-PI and Bland-Altman analysis. Inter- and intrarater analysis was performed. The fat fractions from the accelerated acquisitions had tight 95% limits of with no bias. The fat fractions were acceptable up to a factor of 3.8×, shortening the breath-hold from 17.7s to 4.7s.

This abstract and the presentation materials are available to members only; a login is required.

Join Here