Louis W Mann1, David M Higgins2, Carl N Peters1, Sophie Cassidy1, Ken K Hodson1, Anna Coombs1, Roy Taylor1, and Kieren Grant Hollingsworth1
We compared hepatic fat fractions quantified with
accelerated magnetic resonance (MR) imaging reconstructed with combined
compressed sensing and parallel imaging (CS-PI) with conventional acquisitions.
Undersampled data at ratios of 2.6×, 2.9×, 3.8×, and 4.8× were prospectively
acquired from eleven subjects with type 2 diabetes and a healthy control. Fat
fraction maps were calculated using CS-PI and Bland-Altman analysis. Inter- and
intrarater analysis was performed. The fat fractions from the accelerated acquisitions
had tight 95% limits of with no bias. The fat fractions were acceptable up to a
factor of 3.8×, shortening the breath-hold from 17.7s to 4.7s.