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Abstract #4226

Reconstructing all physical quantities from time-domain data of a very short sequence

Alessandro Sbrizzi1, Annette van der Toorn1, Hans Hoogduin1, Peter R Luijten1, and Cornelis AT van den Berg1

1UMC Utrecht, Utrecht, Netherlands

Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) aims at reconstructing all physical quantities (T1,T2, PD, etc) directly from the data in the time-domain. By solving a large scale nonlinear inversion problem, the parameters can be inferred. The spatial encoding is entangled implicitly in the time response of the system. A very quick acquisition can be performed and processed to derive all system parameters, including electromagnetic field maps like B0 and B1. We illustrate MR-STAT at high resolution for a realistic numerical phantom and we show high precision reconstructions of quantitative maps.

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