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Abstract #4237

Whole-Brain Gray Matter Imaging Exploiting Single-Slab 3D Dual-Echo TSE With Relaxation Modulation: Comparison With Double Inversion Recovery Gray Matter Imaging

Hyunyeol Lee1 and Jaeseok Park2

1Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Korea, Republic of, 2Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

In this work we propose a novel, GM-selective single-slab 3D dual echo TSE with relaxation modulation (no long IR), in which white matter signals remain nulled before signal encoding while CSF signals are modulated to be cancelled during residual reconstruction between echoes with sparsity prior. We demonstrate the effectiveness of the proposed method over conventional DIR in that the former can achieve 1mm-isotropic whole-brain GM acquisition in 5-6 min. without apparent artifacts.

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