Abstract #4240

High Spatiotemporal Resolution 3D Dynamic MRI using Spiral Acquisition and Compressed Sensing with L0 Homotopic Minimization

Lyu Li¹, Sheng Fang², Pascal Spincemaille³, Bida Zhang⁴, Yi Wang^3,5, and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Enginnering, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, ²Institute of nuclear and new energy technology, Tsinghua University, Beijing, China, People's Republic of, ³Radiology, Weill Cornell Medical College, New York, NY, United States, ⁴Healthcare Department, Philips Research China, Shanghai, China, People's Republic of, ⁵Biomedical Engineering, Cornell University, New York, NY, United States

High spatiotemporal resolution 3D imaging is a desired technique for detecting dynamic information of detailed anatomy and getting accurate modeling parameters. In this abstract, we developed a method using golden angle spiral and compressed sensing with L0 homotopic minimization for high resolution 3D imaging. In this method, a high undersampling rate and high motion insensitivity can be achieved. In clinical applications such as dynamic contrast enhanced MRI, this new method is very promising to achieve high spatiotemporal resolution without breath-hold.

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