Abstract #4284

Chemical Shift based Fat-Water Separation using a Variational Approach for B0-field Correction

Andreas Lesch¹, Kristian Bredies², Clemens Diwoky³, and Rudolf Stollberger^1,4

¹Institute of Medical Engineering, Graz University of Technology, Graz, Austria, ²Institute of Mathematics and Scientific Computing, University of Graz, Graz, Austria, ³Institute of Molecular Biosciences, University of Graz, Graz, Austria, ⁴BioTechMed Graz, Graz, Austria

In this work we present an approach for chemical shift based fat/water-separation using variational methods for the estimation of the underlying B₀-field inhomogeneity. We show that the fat/water-problem can be solved by the application of total-generalized-variation (TGV) regularization on the underlying B₀-field to enforce piecewise smoothness. With this approach we are able to model huge B₀-deviations as well as discontinuities in the B₀-field at tissue boundaries with different susceptibility parallel to the main-field. This is shown on different datasets, including two of the ISMRM fat/water-challenge of 2012.

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