Rosie Goodburn1, Nicholas Powell2,3, James O’Callaghan2, Simon Walker-Samuel2, and Karin Shmueli1
1Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom, 2UCL Centre for Advanced Biomedical Imaging, Division of Medicine, London, United Kingdom, 3UCL Centre for Medical Imaging Computing, London, United Kingdom
Susceptibility artifacts hamper gradient-echo
MRI of the mouse brain at 9.4 Tesla. Here, we characterised and modelled
magnetic field maps aiming to improve preclinical mouse MRI. To characterise
field perturbations, we measured and coregistered field maps in 7 mice to
create a group-average field map. Next, a Fourier forward model was used to
simulate a field map based on a susceptibility distribution constructed from
the group-average magnitude image. The measured and modelled field maps showed
similar qualitative field patterns, especially around the aural air cavities,
but had quantitative differences. Work is ongoing to improve the accuracy of
the model.
