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Abstract #4320

Direct CT conversion from a single ultra-short echo sequence

Soumya Ghose1, Jason Dowling1, Robba Rai2, Benjamin Schmitt3, and Gary Liney2,4,5,6

1eHealth, CSIRO, Brisbane, Australia, 2Liverpool Cancer Therapy Centre, Liverpool, Australia, 3Siemens Healthcare Pty Ltd, Macquarie Park, Australia, 4Medical Physics, Ingham Institute, Liverpool, Australia, 5UNSW Australia, Liverpool, Australia, 6University of Wollongong, Wollongong, Australia

Accurate conversion of MRI into attenuation correction maps is of current interest in PET-MR and MR-only radiotherapy planning in particular, where electron density calculation is particularly demanding and usually derived from CT. MRI methods to date have usually involved building a patient atlas and/or use of multiple imaging sequences and are time intensive. We propose a new single sequence approach based on ultra-short echo time to identify tissue classes of air, bone and soft-tissue in combination with a dynamic clustering regression based model that provides a direct CT conversion which is both efficient and accurate.

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