Abstract #4395

Magnetisation Transfer Ratio (MTR) Measurements in the Lumbar cord: A Pilot Study using ZOOM-EPI at 3T

Rebecca Sara Samson¹, Marco Battiston¹, Claudia Angela Michela Gandini Wheeler-Kingshott^1,2, and Marios C Yiannakas¹

¹NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, University College London, London, United Kingdom, ²Brain Connectivity Center, C. Mondino National Neurological Institute, Pavia, Italy

The Magnetisation Transfer Ratio (MTR), and quantitative Magnetisation Transfer (MT) parameters have proven to be sensitive to the diseased spinal cord (SC), however in vivo quantitative imaging of the cord is challenging. Rapid acquisition sequences such as Echo Planar Imaging (EPI) are desirable but may suffer from artefacts and image distortions. Here we present results from the use of single-shot ZOOM-EPI to reduce acquisition time and distortions in SC MTR mapping. The mean SC MTR value for 9 subjects was 38.8 (±4.05). The mean scan-rescan coefficient of variation for measuring SC MTR (from 5 subjects) was 4.39%.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.