Zhiwei Shen1, Yanlong Jia1, Tingting Nie1, Tao Zhang1, Gen Yan1, and Renhua Wu1
Diabetic peripheral neuropathy (DPN) is
one of the main complications of long-term diabetes and the incidence is 60% to
90%. However, there is no objective noninvasive method to detect the degree of damage of DPN and its pathogenesis remains unknown. Functional magnetic
resonance imaging (fMRI) has the advantages of high spatial and temporal
resolution, which had been used to detect neuron activity. In this study, the activation in the lumbar spinal cord of by electric stimulation were detected. Elevated activation percentage
changes of DPN were found and the activation changes have the correlated relatioship with blood biochemical indexes such as glucose, the total cholesterol and haemoglobin A1c.