Abstract #4467

Associations between quantitative MRI biomarkers in the lumbar spine and pain in chronic low back pain patients with disc degeneration

Volkan Emre Arpinar¹ and L Tugan Muftuler^1,2

¹Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States, ²Center for Imaging Research, Medical College of Wisonsin, Milwaukee, WI, United States

Associations between quantitative MRI biomarkers in the lumbar spine and pain in chronic low back pain patients (CLBP) were studied. These biomarkers are currently being explored as quantitative metrics of disc degeneration. Since most CLBP cases are associated with pathologic disc degeneration processes, these biomarkers might provide clues about the actual source of pain. For analysis, the discs from each subject were pooled from the least to the most degenerated one using a semi-quantitative metric. Results showed that these biomarkers might aid in identifying the source of pain in CLBP patients.

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