Abstract #4474

High-Resolution DWI of the Lumbar Plexus using B1-insensitive Velocity-Compensated Diffusion-Prepared 3D TSE

Barbara Cervantes¹, Dominik Weidlich¹, Hendrik Kooijman², Ernst Rummeny¹, Axel Haase³, Jan S Kirschke⁴, and Dimitrios C Karampinos¹

¹Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany, ²Philips Healthcare, Hamburg, Germany, ³Zentralinstitut für Medizintechnik, Garching, Germany, ⁴Neuroradiology, Technische Universität München, Munich, Germany

Diffusion weighted imaging (DWI) can describe the microstructure of nerve fibers and is therefore a powerful tool in the study of neuropathic changes. Diffusion imaging in the body faces challenges with motion and B0 and B1 field effects. Particularly, imaging of nerves has resolution requirements that can limit the performance of the acquisition method. The lumbar plexus is a particularly difficult region to image due to the complexity of the nerve geometry there and its susceptibility to motion and field inhomogeneity. Therefore, careful considerations need to be taken in the design of a diffusion-prepared sequence for imaging the lumbar plexus. The present work proposes an adiabatic diffusion preparation module in combination with a 3D TSE readout to achieve high-resolution DWI of the lumbar plexus.

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