Abstract #4530

High-Resolution DTI of Distal Peripheral Nerves Using Flow-Compensated Diffusion-Prepared 3D TSE

Barbara Cervantes¹, Qinwei Zhang², Kim van de Ven³, Hendrik Kooijman⁴, Ernst Rummeny¹, Axel Haase⁵, Gustav J Strijkers², Jan S Kirschke⁶, Aart J Nederveen², and Dimitrios C Karampinos¹

¹Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany, ²Radiology, Academic Medical Center, Amsterdam, Netherlands, ³Philips Healthcare, Best, Netherlands, ⁴Philips Healthcare, Hamburg, Germany, ⁵Zentralinstitut für Medizintechnik, Garching, Germany, ⁶Neuroradiology, Technische Universität München, Munich, Germany

Quantitative MRI is becoming a promising tool in the assessment of peripheral nerve pathologies and anomalies. Peripheral neuropathy is frequently accompanied by neuropathic changes, which can be quantified with diffusion tensor imaging (DTI). Given the small sizes and oblique geometries of many peripheral nerves, peripheral-nerve DTI requires an acquisition method that can provide high-resolution, distortion-free images in acceptable clinical scanning times. The present work demonstrates isotropic- and sub-millimeter-resolution, artifact-free DTI of the nerves in the lower extremity using flow-compensated diffusion-prepared 3D turbo spin echo (TSE).

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