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Abstract #4530

High-Resolution DTI of Distal Peripheral Nerves Using Flow-Compensated Diffusion-Prepared 3D TSE

Barbara Cervantes1, Qinwei Zhang2, Kim van de Ven3, Hendrik Kooijman4, Ernst Rummeny1, Axel Haase5, Gustav J Strijkers2, Jan S Kirschke6, Aart J Nederveen2, and Dimitrios C Karampinos1

1Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany, 2Radiology, Academic Medical Center, Amsterdam, Netherlands, 3Philips Healthcare, Best, Netherlands, 4Philips Healthcare, Hamburg, Germany, 5Zentralinstitut für Medizintechnik, Garching, Germany, 6Neuroradiology, Technische Universität München, Munich, Germany

Quantitative MRI is becoming a promising tool in the assessment of peripheral nerve pathologies and anomalies. Peripheral neuropathy is frequently accompanied by neuropathic changes, which can be quantified with diffusion tensor imaging (DTI). Given the small sizes and oblique geometries of many peripheral nerves, peripheral-nerve DTI requires an acquisition method that can provide high-resolution, distortion-free images in acceptable clinical scanning times. The present work demonstrates isotropic- and sub-millimeter-resolution, artifact-free DTI of the nerves in the lower extremity using flow-compensated diffusion-prepared 3D turbo spin echo (TSE).

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