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Abstract #0080

Effects of RF pulse profile and within-slice phase dispersion on accuracy of MR fingerprinting with balanced SSFP readout

Su-Chin Chiu1, Te-Ming Lin2, Jyh-Miin Lin3,4, Hsiao-Wen Chung5, Cheng-Wen Ko6, Martin B├╝chert7, and Michael Bock7

1National Taiwan University, Taipei, Taiwan, 2Radiology, Veterans General Hospital, Taipei, Taiwan, 3Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 4Radiology, University of Cambridge, Cambridge, United Kingdom, 5Electrical Engineering, National Taiwan University, Taipei, Taiwan, 6Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan, 7Radiology, University Medical Center Freiburg, Freiburg, Germany

To investigate the effects of within-slice phase dispersion and RF pulse profile on quantitative relaxation mapping using MR fingerprinting with balanced steady-state free precession readout, simulations based on Bloch equations were performed assuming uniform distributions of off-resonance frequency (widths from 0, 1.0, to 2.0 Hz) and imperfect slice profiles of sinc-shaped RF pulses without and with side lobes. Results showed that slight within-slice phase dispersion by 1 to 2 Hz resulted in prominent T2 under-estimations, particularly at large T2 values. Slice profile imperfection led to under-estimations of T1, which became greater as regional off-resonance frequencies increased.

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