Abstract #0138

Highly accelerated DCE imaging with integrated T1 mapping

R Marc Lebel^1,2,3, Yi Guo⁴, Sajan Goud Lingala⁴, RIchard Frayne^2,3, and Krishna S Nayak⁴

¹GE Healthcare, Calgary, AB, Canada, ²Radiology, University of Calgary, Calgary, AB, Canada, ³Seaman Family Centre, Calgary, AB, Canada, ⁴Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Dynamic contrast enhanced (DCE) MRI requires accurate and precise baseline T₁ and M₀ maps for pharmacokinetic modeling. Advances in dynamic acquisitions and reconstructions have enabled high resolution DCE imaging with full anatomical coverage. Rapidly obtaining high SNR T₁/M₀ maps with the same spatial resolution has become a limiting factor for advanced DCE methods. We present a single highly accelerated acquisition that first performs the T₁/M₀ mapping then dynamic imaging. A model-based reconstruction is used to estimate the T₁/M₀ maps. This method makes effective use of scan time and generates maps that are superior to separately acquired ones.

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