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Abstract #0138

Highly accelerated DCE imaging with integrated T1 mapping

R Marc Lebel1,2,3, Yi Guo4, Sajan Goud Lingala4, RIchard Frayne2,3, and Krishna S Nayak4

1GE Healthcare, Calgary, AB, Canada, 2Radiology, University of Calgary, Calgary, AB, Canada, 3Seaman Family Centre, Calgary, AB, Canada, 4Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Dynamic contrast enhanced (DCE) MRI requires accurate and precise baseline T1 and M0 maps for pharmacokinetic modeling. Advances in dynamic acquisitions and reconstructions have enabled high resolution DCE imaging with full anatomical coverage. Rapidly obtaining high SNR T1/M0 maps with the same spatial resolution has become a limiting factor for advanced DCE methods. We present a single highly accelerated acquisition that first performs the T1/M0 mapping then dynamic imaging. A model-based reconstruction is used to estimate the T1/M0 maps. This method makes effective use of scan time and generates maps that are superior to separately acquired ones.

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