When diffusion MRI data is acquired with 3D multi-slab and/or multi-shot imaging techniques, scan times are often lengthy and phase variations between the acquired shots and/or slice-encoding planes of 3D slabs introduce severe motion artifacts in slice images. To accelerate the acquisition of high spatial resolution diffusion MRI volumes with high SNR and fidelity, we outline a 3D image reconstruction model that simultaneously accounts for both in-plane and through-plane motion artifacts in 3D multi-band, multi-slab and multi-shot diffusion data. Diffusion data acquired and reconstructed in this fashion can be acquired at sub-millimeter spatial resolution with high SNR in ~1-2min.
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