Abstract #0197

CEST Fingerprinting: A Novel Approach for Exchange Rate Quantification

Zhengwei Zhou^1,2, Pei Han³, and Debiao Li^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, ³Department of Engineering Physics, Tsinghua University, Beijing, People's Republic of China

In this work, we developed a CEST fingerprinting technique for exchange rate quantification. This method utilizes CEST saturation with varying B₁ amplitudes and durations to create uniqueness of signal evolution for different exchange rates. The acquired signal was matched to a predefined dictionary. Preliminary studies were performed in phantoms to show the feasibility.

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