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Abstract #0197

CEST Fingerprinting: A Novel Approach for Exchange Rate Quantification

Zhengwei Zhou1,2, Pei Han3, and Debiao Li1,2

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, 3Department of Engineering Physics, Tsinghua University, Beijing, People's Republic of China

In this work, we developed a CEST fingerprinting technique for exchange rate quantification. This method utilizes CEST saturation with varying B1 amplitudes and durations to create uniqueness of signal evolution for different exchange rates. The acquired signal was matched to a predefined dictionary. Preliminary studies were performed in phantoms to show the feasibility.

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