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Abstract #0275

Determinants of Symptomatic Intracranial Atherosclerotic Plaque Enhancement on 3D DANTE T1-SPACE Vessel Wall MRI and Relationship to Recurrent Stroke or TIA

Adam de Havenon1, Nabeel Chauhan1, Seong-Eun Kim2, J. Rock Hadley2, Ka-Ho Wong1, David Tirschwell3, Jennifer J. Majersik1, Dennis Parker2, and J. Scott McNally2

1Neurology, University of Utah, Salt Lake City, UT, United States, 2Radiology, University of Utah, Salt Lake City, UT, United States, 3Neurology, University of Washington, Seattle, WA, United States

Intracranial atherosclerotic enhancement on vessel wall MRI is associated with with symptomatic plaque, but there is insufficient data on the clinical characteristics associated with atherosclerotic enhancement on T1-weighted vessel wall MRI sequences or the relationship between atherosclerotic enhancement and recurrent stroke or TIA. Our study demonstrates that intracranial atherosclerotic plaque enhancement detected on 3T vessel wall MRI with 3D DANTE T1-SPACE accurately predicts a high risk of early stroke or TIA recurrence, with a potentially modifiable risk factor: elevated serum hemoglobin A1c.

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