Abstract #0333

Whole-Brain Vessel Wall MR Imaging Using Inversion-Recovery Prepared SPACE: Reproducibility and Accuracy of Intracranial Artery Morphology

Na Zhang^1,2, Fan Zhang¹, Zixin Deng¹, Qi Yang¹, Xiaoming Bi³, Debiao Li¹, Xin Liu², and Zhaoyang Fan¹

¹Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, ²Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China, ³Siemens Healthcare

Intracranial atherosclerosis disease is one of the main causes for cerebrovascular events. A T1-weighted whole-brain vessel wall imaging method, inversion-recovery prepared SPACE (IR-SPACE), was developed at 3T demonstrating advantages over conventional SPACE. This study was aimed to determine the reproducibility of scan-rescan, intra-, and inter-observer as well as the accuracy when using the technique for morphology assessment of the intracranial vessel wall. In general, this study demonstrated excellent reproducibility and good agreement between the 3D and 2D techniques. In conclusion, IR-SPACE is a reproducible and accurate MR method for intracranial vessel wall imaging.

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