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Abstract #0335

Non-Gadolinium-Contrast Relaxation-Enhanced MR Angiography in Children with an Inversion Recovery and T2-Prepared 3D mDIXON Gradient-Echo Technique: Preliminary Experience

Amber L. Pokorney1, Jonathan M. Chia2, Dianna ME Bardo1, Mittun Patel1, Smita S. Bailey1, Scott Jorgensen1, Deepa Biyyam1, Scott Willard1, Jeffrey H. Miller1, Houchun Harry Hu1, and Masami Yoneyama3

1Radiology, Phoenix Children's Hospital, Phoenix, AZ, United States, 2Philips HealthTech, Dallas, TX, United States, 3Philips Electronics, Tokyo, Japan

We demonstrate the preliminary clinical feasibility and utility of a 3D non-Gadolinium MR angiography sequence called REACT (Relaxation-Enhanced MR Angiography without Contrast and Triggering) in 21 pediatric patients (age range: 1.7 – 16.1 years). REACT, which collectively utilizes T2-preparation, inversion recovery, and water-fat separation to suppress unwanted signals and exploit the long T1 and T2 times of unenhanced blood, is particularly beneficial in children, a population where Gadolinium administration should be minimized given recent concerns with residual intracranial Gadolinium deposition. We illustrate and compare REACT to Gadolinium-based MRA in the neck, upper and lower extremities, and the chest, abdomen, and pelvis.

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