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Abstract #0372

7T Diffusion Tensor Imaging of High Mechanical Stress Achilles Tendon-to-Bone Interface

Simone Angela Winkler1, Lara Kuntz1,2, Christoph Leuze1, Hossein Nejadnik1, Laura J Pisani1, and Heike Daldrup-Link1

1Dept of Radiology, Stanford University, Stanford, CA, United States, 2Clinics of Orthopedics and Chair of Cellular Biophysics, Technische Universitaet Muenchen, Munich, Germany

We present imaging analysis using MRI of the Achilles tendon-to-bone interface (“enthesis”) to investigate on the four distinct zones responsible for mechanical force transfer. Conventional T1- and T2-weighted imaging in humans yields very low MR signal. We therefore present T1-weighted FLASH 3D imaging at ultra high-field (7T), using a porcine sample from a minipig leg. We were able to identify the four zones (fibrous connective tissue, uncalcified fibrocartilage, calcified fibrocartilage, and bone) in both T1 and diffusion tensor imaging (DTI).

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