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Abstract #0384

High resolution imaging by phase encoded xSPEN MRI

Zhiyong Zhang1, Michael Lustig2, and Lucio Frydman1

1Department of Chemical Physics, Weizmann Institute of Science, Rehovot, Israel, 2Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, United States

We have recently introduced cross-term SPatiotemporal ENcoding (xSPEN), a technique with exceptional resilience to field heterogeneities. Like other single-shot methods, however, xSPEN’s resolution and SNR are intrinsically limited. This study explores a multi-scan, phase-encoded extension of xSPEN, which improves sensitivity while increasing resolution along both the phase-encoded and the slice-selection dimensions simultaneously. This reflects xSPEN’s unusual kernel whereby a y-axis can be sampled by a z-gradient and viceversa. Furthermore, as each phase-encoded xSPEN scan provides an entire 2D image, each low-resolution xSPEN scan in the set may be used to correct motions leading to very high definition 3D MRI capabilities.

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