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Abstract #0423

k-t accelerated aortic 4D flow MRI in under 2 minutes: feasibility and impact of resolution, k-space sampling patterns, and respiratory navigator gating on hemodynamic measurements

Emilie Bollache1, Alex J. Barker1, Jeremy D. Collins1, Pim van Ooij2, Rouzbeh Ahmadian1, Alex Powell1, James C. Carr1, Julia Geiger1, and Michael Markl1,3

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 3Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

Our objective was to assess the performance of eight highly k-t accelerated non-gated free-breathing aortic 4D flow MRI measurements acquired in under 2 minutes (PEAK GRAPPA R=5; TRes=67.2ms; four ky-kz-space Cartesian fillings: linear, center-out, out-center-out, random; two spatial resolutions=3.5x2.3x2.6mm3, 4.5x2.3x2.6mm3), both in vitro and in 10 healthy volunteers. Despite lower image quality, the significantly shorter k-t accelerated datasets provided aortic hemodynamic indices in agreement with conventional respiratory-gated 4D flow measurements. Differences were non-significant when using linear and out-center-out k-space samplings (absolute differences≤22%). In conclusion, aortic 4D flow MRI in under 2 minutes is feasible with moderate underestimation of flow indices.

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